363 Increased Frequency of γδ T Cells in Patients with Allergic Conjunctivitis

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363 Increased Frequency of γδ T Cells in Patients with Allergic Conjunctivitis

tal General de México, Mexico City, Mexico. Background: Giant papillary conjunctivitis is associated with soft and rigid contact lens wearing, ocular prostheses, exposed sutures, extruded scleral buckle, filtering blebs, band keratopathy, corneal foreign bodies, limbal dermoids, and cyanoacrylate tissue adhesives. Patients present decreased lens tolerance, increased lens movement and awareness,...

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57 Increased Frequency of CD4+ CCR4+ CCR9+ Cells in Patients With Allergic Conjunctivitis

mean hyperemia with CAPT was 2.3 6 0.6 units (between moderate and severe) and with EEC was 1.9 6 0.5 units (approximately moderate); these maxima occurred after 30 minutes with CAPT (rapid spike) and after 180 minutes with EEC (gradual increase). Mean swelling was ,1 unit out of 4 units at all times (CAPT and EEC), and mucous discharge was observed in only 1 subject during the study (with CAPT...

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γδ T cells are required for maximal expression of allergic conjunctivitis.

PURPOSE To determine the function of γδ T cells in early- and late-phase responses in allergic conjunctivitis. METHODS Wild-type (WT) C57BL/6 and γδ T cell-deficient (TCR-δ(-/-)) mice were immunized intraperitoneally and challenged topically for 7 consecutive days with short ragweed pollen. Natural killer T (NKT) and γδ T cell-double-deficient mice were generated by treating TCR-δ(-/-) mice w...

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56 Increased Frequency of CD4+ CD25+ FOXP3- in Allergic Conjunctivitis Patients

mean hyperemia with CAPT was 2.3 6 0.6 units (between moderate and severe) and with EEC was 1.9 6 0.5 units (approximately moderate); these maxima occurred after 30 minutes with CAPT (rapid spike) and after 180 minutes with EEC (gradual increase). Mean swelling was ,1 unit out of 4 units at all times (CAPT and EEC), and mucous discharge was observed in only 1 subject during the study (with CAPT...

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Activated T cells in an animal model of allergic conjunctivitis.

The aim of this study has been to determine whether the presence of lymphocytic infiltrates observed in the histology of ocular allergic conditions in humans or in the late phase of ocular anaphylactic reactions in experimental animals is a non-specific event dependent only on the degranulation of mast cells, or is conditioned by a specific response to antigen. With this in mind, responses to a...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2012

ISSN: 1939-4551

DOI: 10.1097/01.wox.0000412126.72016.4b